The Protein Language is simpler than the DNA language. The DNA language has 64 different sounds whereas the protein language is composed of the 20 sounds. Each amino acid in the sequence says a different word and together they make up a language.
Proteins are composed of a series of amino acids to form a poly peptide, and their sequence determines the molecular function of the protein.
The amino acids that form the sequence are each given a scientific letter to differentiate them. These are
A Alanine
C Cysteine
D Aspartic Acid
F Phenylalanine
G Glycine
H Histidine
I Isoleucine
K Lysine
L Leucine
M Methionine
N Asparagine
P Proline
Q Glutamine
R Arginine
S Serine
T Threonine
V Valine
W Tryptophan
A typical protein has a peptide sequence such as
MLFRCSMSBTFLLBSV
This cannot be read because it is a list of consonants.
However if we insert a vowel after each consonant then we have the basis of a language that can be read and listened to.
Using only the vowel "a" we get the series of sounds
Ma La Fa Ra Ca Sa Ma Sa Ba Ta Fa La La Ba Sa Va
However we do not know that the consonant sounds are correct, since each of the letters has been arbitrarily assigned. Typically the latter assignment had been the first letter of the amino acid e.g. Leucine becomes L and Isoleicine becomes I.
Assignment of the sounds
V is for Valine
Lets start with Valine. It is called valine because the molecule has the shape of a letter V. So the actual shape of the Valine moleculae is a letter V. Every time valine appears in an amino acid sequence it is spelling out the letter V. Since Valine makes a V shape letter the sound Va is assigned to Valine.
This forms the first letter of the delta alphabet Va, Bi, Go Ja from which can be derived that if Va is Valine then Bi is Alanine, Go is Glutamic Acid, and Ja is Glycine.
Next in letter shapes is Leucine. This amino acid makes the L shape of the greek Lambda symbol, and is therefore assigned as the letter L, with the sound La.
This forms the first letter of the beta alphabet La, Ra, Qua, Da so that with Leucine as La, Proline is Ra, Glutamine is Qua, and Arginine is Da.
The first aphabet begins with Fa for Phenylalanine. This froms the alphabet Fa, Si, Yo, Wi so that with phenylalanine as Fa, Serine is Si, Tyrosine is Yo and Tryptophan is Wi
The gamma alphabet is formed from the sounds Chee, To, Ki, Ma. Here Isoleucine is Chee, Threoine is To, Lysine is Ki, and Ma is transcribed into Da.
A Alanine = Bi
C Cysteine = Zi
D Aspartic Acid = Ga
F Phenylalanine = Fa
G Glycine = Ja
H Histidine = Shi
I Isoleucine = Chee
K Lysine = Ki
L Leucine = La
M Methionine = Me
N Asparagine = Nu
P Proline = Ra
Q Glutamine = Qua
R Arginine = Da
S Serine = Si
T Threonine = To
V Valine = Va
W Tryptophan = Wi
Many of these sounds remain in accordance with the letter that is their scientific assignment e.g. Leucine is La, Serine is Si.
However some are completely different to their one-letter code such as Alanine being Bi, and Cysteine being Zi.
Here is an example of the language translated from the amino acid sequence for a protein called “Babilovine” of the “Sharkin” family from Human Chromosome 17:
Me Ba Bi Love Vu Dear Rib Bud Day Fay Va Vu Dear Ray La Lon Quiv Va Von Queen Bud Wing Gal Lon
Ga Bud Du Dud Wi Vu Deb Bar Lady Du Dye Si Ray Von Kave Va Va Fair Rice Seed Jon Go Va Von Go Quack Kad Deb Bear Rod Jack Kin Quar Room Mon Key Bear Rice Son God Bless Mary Bon Queen Go Quad Don Go Kin Quar Ray Lon Go Goose Mary Beast Seed Deb Bear Rice Sis To Wing Go Goose Seed Jay Lady Don Yo Gay Key Boy Yes Rod Jon Gester Du Day Li Si Save Vay Me Touch Chief Von Kiss Seed Dear Rah Feed Don Go Kin Quad Jack Katch Char La Lon God Ju Du Day Latch Chee Son Ga Baby Lock Key Bud Jeb Bi Va Rock Kay Me Fa Fa Face Seed Day Lon Go Ya Lock King Go Li Ray Von Gay Kay Lock Kad Jar Venus Say Latch Chick Kave Von Kay Fone Go Gay Chick King Gester Wits Son Gal Love Vit To Ron Quad Jay Chime Me Jay Chief Farm Bon Key Ron Gay Shi Von Kay Me Toy Yes Rock Kit To Quill Lon Queen She Say Li Ray La La Latch Chee Zing Gay Nut Lady Don Gear Rod Jon Nut Lord Jet Touch Char Lady Dye Mary Ba Bud Jeb Bud Judj Zeus Son Kave Vani La Left Tay Kad Judj Zave Von Ga Bud Wing God Rock Kave Vani Lady Deb Bud Jay Me Jeb Bon Shay Feed Day Me Ray Char Chick Nani Nut Lon God Wing Go Ta Va Ron Nut Ya Li Ra Ron Gest Tut Day Von Ya Vib Bon Gay Nut Zoo Jay Loy Yes Bon Queen Bon Go Me Son Nut Key Beast Son Gay She Ju Wi Vhuman Zing Gay Quad Day Vay Me Kay Fish Shark Kin Yo Go Go Go Go Gay Von Go To Jeb Beast Son Queen Gester Will Li Ron Shi Von Go Von Quarius Soy Yo Gemini Son Gester Witt Tongue says Good Bear Rab Ba Bi Va Vinch Charm Ja Jon Go Toy Yo Jar Venus Say Lon Goose Say Lon Quill Lamb Bon Goose Sis To Ja Jack Kad Day La Latch Cheer Ray Va Va Rod Jar Von Gemini Say Lon Nest Mary Beam Me Ba Beast Saturn Char La Life Fone God Jack Kad Don Quill Lady Mum Ju Deb Bon Go Gal Li Seed Don Gester Dye Soy Yoni Shi Noah sharkin;
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